Associations of PNPLA3 and LEP genetic polymorphisms with metabolic-associated fatty liver disease in Thai people living with human immunodeficiency virus

doi:10.4254/wjh.v16.i3.366

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Mar 27, 2024 (publication date) through May 12, 2024

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World Journal of Hepatology

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1948-5182

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World J Hepatol. Mar 27, 2024; 16(3): 366-378
Published online Mar 27, 2024. doi: 10.4254/wjh.v16.i3.366

Table 7 Logistic regression analysis of factors associated with metabolic-associated fatty liver disease (people living with human immunodeficiency virus and metabolic-associated fatty liver disease vs people living with human immunodeficiency virus and non-metabolic-associated fatty liver disease)

Factor	Exp(B)	95%CI	P value
AST	4.615	1.081-19.709	0.039^a
Fasting Plasma glucose	21.5	5.327-86.767	< 0.001^a
Triglyceride	6.747	1.747-26.047	0.006^a
Total cholesterol	0.125	0.019-0.819	0.030^a
LDL	12.97	1.983-84.827	0.007^a
APOB rs10495712	4.195	1.304-18.532	0.019^a
APOA5 rs662799	0.012	0.002-0.770	< 0.001^a
LEP rs7799039	0.321	0.070-1.469	0.143^a

^aP value < 0.2. AST: Aspartate aminotransaminase; LDL: Low-density lipoprotein.

Citation: Choochuay K, Kunhapan P, Puangpetch A, Tongsima S, Srisawasdi P, Sobhonslidsuk A, Sungkanuparph S, Biswas M, Sukasem C. Associations of PNPLA3 and LEP genetic polymorphisms with metabolic-associated fatty liver disease in Thai people living with human immunodeficiency virus. World J Hepatol 2024; 16(3): 366-378
URL: https://www.wjgnet.com/1948-5182/full/v16/i3/366.htm
DOI: https://dx.doi.org/10.4254/wjh.v16.i3.366