Morphological aspects of small-duct cholangiopathies: A minireview

doi:10.4254/wjh.v15.i4.538

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Apr 27, 2023 (publication date) through May 11, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Apr 27, 2023; 15(4): 538-553
Published online Apr 27, 2023. doi: 10.4254/wjh.v15.i4.538

Table 3 Ductal plate malformation – genes and encoded proteins

Disorder	Gene	Product
ARPKD	PKHD	Fibrocystin/polyductin
ADPKD	PKD1	Polycystin 1
	PKD2	Polycystin 2
	GANAB/PKD3	Glucosidase II alpha subunit
PCLD	PRKCSH	Glucosidase II beta subunit
	ALG8	Alpha-1,3-glucosyltransferase
	SEC61B	SEC61 translocon subunit beta
	SEC63	Translocon component in the endoplasmic reticulum
	LRP5	LDL receptor-related protein 5
CHF-SC	ZFYVE19	Zinc finger FYVE-type containing 19

ARPKD: Autosomal recessive polycystic kidney disease; ADPKD: Autosomal dominant polycystic kidney disease; PCLD: Polycystic liver disease (without kidney); CHF-SC: Congenital hepatic fibrosis and sclerosing cholangiopathy.

Citation: Sticova E, Fabian O. Morphological aspects of small-duct cholangiopathies: A minireview. World J Hepatol 2023; 15(4): 538-553
URL: https://www.wjgnet.com/1948-5182/full/v15/i4/538.htm
DOI: https://dx.doi.org/10.4254/wjh.v15.i4.538