COVID-19 and liver dysfunction in children: Current views and new hypotheses

Table 2 The frequencies of different coronavirus disease 2019-related liver injury types in adults and children

CRLI types	Liver test parameters[18]	Adults[18]	Children[19]
Hepatocyte type	ALT/AST ≥ 3×ULN	66 (20.8%)	24 (18.5%)
Cholangiocyte type	ALP/GGT ≥ 2×ULN	93 (29.2%)	93 (71.5%)
Mixed type	ALT/AST ≥ 3×ULN and ALP/GGT ≥ 2×ULN	138 (43.4%)	13 (10.0%)

CRLI: Coronavirus disease 2019-related liver injury; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transferase; ULN: Upper limit of normal.