Prognostic role of ring finger and WD repeat domain 3 and immune cell infiltration in hepatocellular carcinoma

Table 2 Detailed information on the statistical correlation between ring finger and WD repeat domain 3 expression and immune cell infiltration

Gene	Immune cell type	Pearson’s correlation coefficient	Pearson’s P value	Spearman’s correlation coefficient	Spearman’s P value
RFWD3	Th2 cells	0.499	< 0.001	0.501	< 0.001
	Th cells	0.434	< 0.001	0.436	< 0.001
	Cytotoxic cells	-0.304	< 0.001	-0.314	< 0.001
	DCs	-0.281	< 0.001	-0.304	< 0.001
	pDCs	-0.261	< 0.001	-0.261	< 0.001
	Neutrophils	-0.210	< 0.001	-0.214	< 0.001
	TFH cells	0.226	< 0.001	0.213	< 0.001
	Tcm cells	0.187	< 0.001	0.164	0.002
	Tgd cells	-0.105	0.043	-0.142	0.006
	Tregs	-0.155	0.003	-0.121	0.019
	aDCs	0.141	0.006	0.114	0.027
	NK CD56bright cells	0.128	0.013	0.112	0.031
	Th17 cells	-0.170	< 0.001	-0.110	0.033
	Eosinophils	0.077	0.135	0.106	0.041
	Macrophages	0.096	0.063	0.071	0.171
	Th1 cells	0.090	0.081	0.064	0.214
	iDCs	-0.034	0.507	-0.061	0.241
	Mast cells	-0.053	0.309	-0.060	0.247
	CD8 T cells	-0.047	0.368	-0.058	0.260
	T cells	-0.013	0.796	-0.033	0.522
	Tem cells	0.085	0.100	0.020	0.704
	B cells	0.033	0.525	0.017	0.744
	NK cells	0.035	0.494	-0.012	0.810
	NK CD56dim cells	0.020	0.699	-0.001	0.979

aDCs: Activated dendritic cells; DCs: Dendritic cells; iDCs: Immature dendritic cells; NK: Natural killer; pDCs: Plasmacytoid dendritic cells; RFWD3: Ring finger and WD repeat domain 3; Tcm: T central memory; Tem: T effector memory; TFH: T follicular helper; Tgd: T gamma delta.