Modified preoperative score to predict disease-free survival for hepatocellular carcinoma patients with surgical resections

Table 1 Clinicopathological characteristics and univariate analysis of 1106 patients

	n (%)	P value
Preoperative variables
Age (yr)		0.202
≤ 55	436 (39)
> 55	670 (61)
Sex		0.098
Male	863 (78)
Female	243 (22)
Viral hepatitis		0.111
No viral hepatitis	185 (17)
Hepatitis B or C or B + C	921 (83)
Child Class		0.964
A/B	1099 (99)
C	7 (1)
Platelet count (103/μL)		0.003
< 100	124 (11)
≥ 100	982 (89)
Total bilirubin (mg/dL)		0.032
≤ 1.3	1010 (91)
> 1.3	96 (9)
PT-INR		0.053
≤ 1.2	1004 (91)
> 1.2	102 (9)
Albumin (g/dL)		0.001
< 3.5	86 (8)
≥ 3.5	1020 (92)
AFP (ng/mL)		0.116
< 200	785 (71)
≥ 200	321 (29)
ICG (%)		< 0.0001
≤ 10	748 (68)
> 10	358 (32)
Multiplicity		< 0.0001
Solitary	852 (77)
Multiple	254 (23)
Radiologic TTV (cm3)		< 0.0001
mean ± SD	113.06 ± 237.13
≤ 32.0	645 (58)
> 32.0	461 (42)
Postoperative variables
Resection margin (cm)		0.082
≤ 1.0	817 (74)
> 1.0	249 (23)
Liver cirrhosis		0.001
No	585 (53)
Yes	521 (47)
Tumor rupture		0.004
No	1076 (97)
Yes	30 (3)
Edmondson-Steiner grade		< 0.0001
I/II	682 (62)
III/IV	424 (38)
Capsule		0.789
No	192 (17)
Yes	914 (83)
Microvascular invasion		< 0.0001
No	786 (71)
Yes	320 (29)
Pathologic TTV (cm3)		< 0.0001
mean ± SD	131.59 ± 293.81
≤ 32.8	652 (59)
> 32.8	454 (41)

PT-INR: International normalized ratio of prothrombin time; AFP: Alpha fetoprotein; ICG: Indocyanine green; TTV: Total tumor volume; SD: Standard deviation.