Baicalin provides protection against fluoxetine-induced hepatotoxicity by modulation of oxidative stress and inflammation

Figure 4 Effect of baicalin on serum bilirubin, total protein and albumin in fluoxetine-induced hepatotoxic rats. A: Serum bilirubin; B: Serum total protein; C: Serum albumin. Group 1: Control rats; group 2: Fluoxetine treated rats (10 mg/kg); group 3: Fluoxetine (10 mg/kg) + baicalin (50 mg/kg); group 4: Fluoxetine (10 mg/kg) + baicalin (100 mg/kg); group 5: Fluoxetine (10 mg/kg) + silymarin (100 mg/kg); group 6: Baicalin (100 mg/kg); group 7: Silymarin (100 mg/kg). Data represent mean ± SD, n = 6. ^aRepresents a significant difference from group 1, P < 0.05; ^brepresents a significant difference compared with group 2, P < 0.05; ^crepresents a significant difference compared with group 2, P < 0.005; ^drepresents a significant difference compared with group 2, P < 0.0001.