Cytomegalovirus infection in liver-transplanted children

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Feb 27, 2022; 14(2): 338-353
Published online Feb 27, 2022. doi: 10.4254/wjh.v14.i2.338

Table 3 Uses of available cytomegalovirus assays

Use	Assay
Diagnosis	CMV viral load by plasma QNAT; CMV viral load by real-time PCR assay; pp65 antigen testing; CMV IgG/IgM antibodies
Diagnosis of tissue-invasive CMV disease	Histopathology
Pre-transplant risk stratification	CMV IgG/IgM antibodies
Threshold for initiation of pre-emptive therapy	CMV viral load by plasma QNAT; Quantitative pp65 antigen measurement; NASBA assay
Monitoring or endpoint (prophylaxis, pre-emptive or treatment)	CMV viral load by plasma QNAT; QuantiFERON-CMV assay
Endpoint of treatment of tissue-invasive CMV disease	Histopathology
Prediction of developing CMV disease	QuantiFERON-CMV assay

CMV: Cytomegalovirus; Ig: Immunoglobulin; PCR: Polymerase chain reaction; QNAT: Quantitative nucleic acid testing.

Citation: Onpoaree N, Sanpavat A, Sintusek P. Cytomegalovirus infection in liver-transplanted children. World J Hepatol 2022; 14(2): 338-353
URL: https://www.wjgnet.com/1948-5182/full/v14/i2/338.htm
DOI: https://dx.doi.org/10.4254/wjh.v14.i2.338

Onpoaree N, Sanpavat A, Sintusek P. Cytomegalovirus infection in liver-transplanted children. World J Hepatol 2022; 14(2): 338-353 [PMID: 35317177 DOI: 10.4254/wjh.v14.i2.338]

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