CLIF-SOFA and CLIF-C scores for the prognostication of acute-on-chronic liver failure and acute decompensation of cirrhosis: A systematic review

Table 5 Acute-on-chronic liver failure vs acute decompensation liver transplantation[45]

	Liver transplantation ACLF	Liver transplantation AD	P value
Total	22 (73.3%)	7 (26.7%)	-
Age (yr)	57.0 (IQR 11.0)	54.0 (IQR 5.0)	n.s.
MELD	30.7 (IQR 5.0)	12.9 (IQR 7.3)	< 0.001
iMELD	53.1 (IQR 8.7)	36.5 (IQR 15.6)	< 0.001
MELD-Na	34.4 (IQR 18.7)	14.3 (IQR 17.6)	0.002
CPC	13.0 (IQR 1.0)	9.0 (IQR 3.0)	< 0.001
SOFA	8.0 (IQR 3.0)	4.0 (IQR 3.0)	< 0.001
CLIF-SOFA	12.0 (IQR 3.0)	5.0 (IQR 3.0)	< 0.001
CLIF-C OF	11.5 (IQR 2.0)	7.0 (IQR 1.0)	< 0.001

ACLF: Acute-on-chronic liver failure; AD: Acute decompensation; MELD: Model of End-Stage Liver Disease; iMELD: integrated MELD; MELD-Na: sodium MELD; CPC: Child-Pugh class; SOFA: Sequential Organ Failure Assessment; CLIF-SOFA: CLIF-Consortium modification of Sequential Organ Failure Assessment; CLIF-C OF: Organ Failure score.