CLIF-SOFA and CLIF-C scores for the prognostication of acute-on-chronic liver failure and acute decompensation of cirrhosis: A systematic review

Table 3 CLIF-SOFA score[64]

Points	0	1	2
Liver Bilirubin (mg/dL)	< 1.2	≥ 1.2 - < 2.0	≥ 2.0 - < 6.0
Renal Creatinine (mg/dL)	< 1.2	≥ 1.2 - < 2.0	≥ 2.0 - < 3.5
Neurological HE grade	-	1	2
Haematological INR	< 1.1	≥ 1.1 - < 1.25	≥ 1.25 - < 1.5
Circulation MAP (mmHg)	≥ 70	< 70	Dopamine ≤ 5 or Dobutamine or Terlipressin
Respiratory PaO2 /FiO2 or SpO2 /FiO2	> 400; > 512	> 300-≤ 400; > 357 - ≤ 512	> 200 - ≤ 300; > 214 - ≤ 357

RRT: Renal Replacement Therapy; HE: Hepatic encephalopathy; INR: International Normalized Ratio; PaO₂: Partial pressure of arterial oxygen; MAP: Mean Arterial Pressure; FiO₂: Fraction of inspired oxygen; SpO₂: Pulse oximetric saturation.