Circulating microRNA 9-3p and serum endocan as potential biomarkers for hepatitis C virus-related hepatocellular carcinoma

Table 3 Correlations between microRNA 9-3p levels and clinical data in hepatocellular carcinoma group

	n	microRNA 9-3p
		Median (IQR)		P value
Vascular invasion
Negative	25	0.04 (0.02-0.26)		0.002
Positive	10	0.02 (0.02-0.02)
LN metastasis
Negative	28	0.04 (0.02-0.17)		0.072
Positive	7	0.02 (0.02-0.03)
Distant metastasis
No	23	0.04 (0.03-0.26)		< 0.001
Yes	12	0.02 (0.02-0.02)
Child Pugh class
A	22	0.03 (0.02-0.04)		0.389
B	13	0.04 (0.02-0.26)
Tumor number
Single	16	0.03 (0.02-0.17)		0.935
Multiple	19	0.03 (0.02-0.05)
Tumor size in cm
Small < 3	7	0.03 (0.02-0.15)		0.852
Medium 3-5	15	0.03 (0.02-0.06)
Large > 5	13	0.04 (0.02-0.04)
Tumor site
Rt lobe	19	0.04 (0.02-0.06)		0.432
Lt lobe	8	0.04 (0.03-0.15)
Both	7	0.02 (0.02-0.04)
Caudate lobe	1
BCLC stage
A	4	0.26 (0.17-0.26)		< 0.001
B	18	0.04 (0.03-0.05)
C	13	0.02 (0.02-0.02)

Rt.: Right; Lt.: Left; BCLC: Barcelona Clinic Liver Cancer; IQR: Interquartile range; LN: Lymph node.