Abnormal liver enzymes: A review for clinicians

Table 4 Non-alcoholic fatty liver disease spectrum

Non-alcoholic fatty liver disease spectrum
NAFL	Steatosis changes. No cellular ballooning, hepatocyte inflammation or fibrosis	Prevalence of 25% approximately. Reversible
NASH	Steatosis changes. Cellular ballooning and hepatocyte inflammation. No fibrosis	Prevalence of 1.5%-6.45% approximately. Generally irreversible (has been found to be reversible in some patients)
NASH related liver cirrhosis	Hepatocyte destruction and fibrosis	Prevalence of 1%-2% approximately. Irreversible
Healthy liver ←→ NAFL → NASH → NASH related cirrhosis

NAFL: Non-alcoholic fatty liver; NASH: Non-alcoholic steatohepatitis.