Acute-on-chronic liver failure in children

Table 5 Modified Asian Pacific Association for the Study of the Liver Acute-on-Chronic Liver Failure score

Points	Total bilirubin (mg/dL)	HE grade	INR	Lactate (mmol/L)	Creatinine (rise from baseline)
1	< 15	0	< 1.8	< 1.5	< 1.5 ×
2	15-25	I-II	1.8-2.5	1.5-2.5	1.5 to ≤ 3 ×
3	> 25	III-IV	> 2.5	> 2.5	> 3 × or need RRT

HE: Hepatic encephalopathy; INR: International normalized ratio; RRT: Renal replacement therapy.