Copyright
©The Author(s) 2021.
World J Hepatol. Jan 27, 2021; 13(1): 109-119
Published online Jan 27, 2021. doi: 10.4254/wjh.v13.i1.109
Published online Jan 27, 2021. doi: 10.4254/wjh.v13.i1.109
Table 2 Allele and genotype frequencies of interferon lambda-4 rs12979860 polymorphism in patients with hepatitis C virus-associated liver diseases and healthy control subjects
| rs12979860 | Control, n = 260 | Total patients, n = 305 | Fibrosis, n = 53 | Cirrhosis, n = 154 | HCC, n = 98 | P value | ||||
| Fibrosis vs Control | Cirrhosis vs Control | HCC vs Control | Fibrosis vs Cirrhosis | Cirrhosis vs HCC | ||||||
| Allele | 0.047 | < 0.001 | 0.010 | 0.708 | 0.618 | |||||
| C | 345 (66.3) | 331 (54.3) | 59 (55.7) | 163 (52.9) | 109 (55.6) | |||||
| T | 175 (33.7) | 279 (45.7) | 47 (44.3) | 145 (47.1) | 87 (44.4) | |||||
| Genotype | 0.113 | < 0.001 | 0.002 | 0.541 | 0.665 | |||||
| CC | 115 (44.2) | 76 (24.9) | 16 (30.2) | 36 (23.4) | 24 (24.5) | |||||
| CT | 115 (44.2) | 179 (58.7) | 27 (50.9) | 91 (59.1) | 61 (62.2) | |||||
| TT | 30 (11.6) | 50 (16.4) | 10 (18.9) | 27 (17.5) | 13 (13.3) | |||||
- Citation: de Bitencorte JT, Rech TF, Lunge VR, dos Santos DC, Álvares-da-Silva MR, Simon D. Association of interferon lambda-4 rs12979860 polymorphism with hepatocellular carcinoma in patients with chronic hepatitis C infection. World J Hepatol 2021; 13(1): 109-119
- URL: https://www.wjgnet.com/1948-5182/full/v13/i1/109.htm
- DOI: https://dx.doi.org/10.4254/wjh.v13.i1.109