Transaminitis is an indicator of mortality in patients with COVID-19: A retrospective cohort study

Table 2 Demographic and baseline characteristics of the study population

Variable	Study population (n = 130)
Age, yr, median (IQR)	62 (48, 73)
Females	59 (45.4)
Body mass index, kg/m2, median (IQR)	28.7 (26, 36)
Smoking	38 (29.2)
Alcohol	30 (23.1)
Diarrhea	34 (26.2)
Nausea	32 (24.6)
Abdominal pain	21 (16.2)
Anorexia	34 (26.2)
Other gastro-intestinal symptoms1	37 (28.5)
X-ray findings2	87 (66.9)
Hypertension	69 (53.1)
Admitted to ICU	58 (44.6)
On ventilator	43 (33.1)
Age-adjusted Charlson Index, median (IQR)	3.5 (1, 6)
On medications with gastro-intestinal side-effects	46 (35.4)
Death	28 (21.5)
Lactic Acid, mean (SD), n = 97	1.7 (1.4)
Lactic acid dehydrogenase, mean (SD), n = 92	424 (182.6)
D-dimer, median (IQR), n = 105	1.7 (0.9, 3.7)
Alanine aminotransferase, IU/L, median (IQR)	29 (16, 53)
Aspartate aminotransferase, IU/L, median (IQR)	39 (23, 68)
Alkaline phosphatase, IU/L, median (IQR)	77 (60, 115)
Total bilirubin, mean (SD)	0.4 (0.3)
Direct bilirubin, mean (SD), n = 92	0.2 (0.1)
Albumin, g/dL, mean (SD)	3.2 (0.8)
Prothrombin time, seconds, mean (SD), n = 81	16.9 (8.1)

¹Other gastro-intestinal symptoms include loss of taste or smell, constipation, dysphagia, reflux and vomiting.

²X-ray findings including ground glass opacities and bilateral infiltrate. All values are reported as n (%), mean (SD) or median (25^th, 75^th). P value: Chi-square test for categorical variables, two-sided t-test for parametric continuous variables and Wilcoxon rank-sum test for nonparametric continuous variables. ICU: Intensive care unit; IQR: Interquartile range.