Comparison of four non-alcoholic fatty liver disease detection scores in a Caucasian population

Table 1 Basic characteristics of the EFFECT and prospective investigation of obesity, energy and metabolism samples

	EFFECT sample		POEM sample
Variable	n	mean ± SD or proportion	n	mean ± SD
Age (yr)	310	64.6 ± 7.2	310	50.1 ± 0.1
Sex (% female)	310	39	310	51
Systolic blood pressure (mmHg)	310	143 ± 17	310	125 ± 16
Weight (kg)	310	90 ± 13	310	80 ± 15
Height (cm)	310	172 ± 9	310	173 ± 10
Waist circumference (cm)	310	107 ± 11	310	92 ± 11
BMI (kg/m2)	310	30.4 ± 3.4	310	26.4 ± 4.3
Diabetes medication (%)	310	41	310	2.2
Statin treatment (%)	310	39	310	4.1
Antihypertensive treatment (%)	310	57	310	7.3
Fasting glucose (mmol/L)	308	7.4 ± 2.0	310	5.09 ± 0.78
Fasting insulin (mU/L)	306	10.9 ± 6.9	309	6.49 ± 9.49
Serum cholesterol (mmol/L)	308	5.51 ± 1.41	310	5.29 ± 1
Serum triglycerides (mmol/L)	308	2.14 ± 1.16	310	1.15 ± 0.7
HDL-cholesterol (mmol/L)	308	1.34 ± 0.37	310	1.39 ± 0.37
LDL-cholesterol (mmol/L)	308	3.47 ± 1.23	310	3.39 ± 0.87
ALT (ukat/L)	307	0.62 ± 0.45	307	0.45 ± 0.15
AST (ukat/L)	301	0.51 ± 0.24	307	0.34 ± 0.15
Liver PDFF (%)	310	13.2 ± 9.5	310	4.2 ± 5.4
NAFLD (%)	310	75	310	23
Metabolic syndrome (%)	308	81	310	15

P < 0.001 for differences between the two samples for all variables except height, LDL and HDL-cholesterol, which did not show statistical significance. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; NAFLD: Non-alcoholic fatty liver disease; PDFF: Proton density fat fraction; POEM: Prospective investigation of obesity, energy and metabolism; SD: Standard deviation.