Obeticholic acid attenuates human immunodeficiency virus/alcohol metabolism-induced pro-fibrotic activation in liver cells

Figure 2 Effects of obeticholic acid on p53 mRNA and reactive oxygen species production in human immunodeficiency virus-infected Huh7. 5-CYP cells exposed to acetaldehyde-generating system. A: p53 mRNA; B: Reactive oxygen species production. All data were obtained from 3 independent experiments and presented as mean ± SEM. Bars with different letters are significantly different at P ≤ 0.05. AGS: Acetaldehyde-generating system; HIV: Human immunodeficiency virus; OCA: Obeticholic acid.