Malnutrition and non-compliance to nutritional recommendations in patients with cirrhosis are associated with a lower survival

Table 3 Univariate and multivariate analysis of factors associated with mortality

Variable	Univariate analysis; OR (95%CI)	P value	Multivariate analysis1; OR (95%CI)	P value
Age	1.03 (1.01-1.06)	0.004	1.03 (1.00-1.06)	0.002
Child-Pugh score	1.13 (1.04-1.23)	0.002	1.09 (0.98-1.20)	0.09
MELD score	1.06 (1.03-1.09)	< 0.001
Presence if malnutrition2	1.82 (1.12-2.94)	0.01
Creatinine (mg/dL)	1.94 (1.46-2.57)	< 0.001	2.13 (1.31-3.45)	0.03
INR	1.60 (1.05-2.43)	0.02
Albumin (g/L)	0.45 (0.29-0.68)	0.01
Cholesterol (mg/dL)	0.99 (0.98-0.99)	0.02
Serum sodium (mEq/L)	0.94 (0.90-0.98)	0.003
Protein intake 1.2-1.5 g/kg/d3	0.51 (0.28-0.90)	0.02	0.40 (0.20-0.77)	0.007

¹In order to avoid collinearity between repeating variables, in model were included: Age, Child-Pugh score, presence of malnutrition, creatinine, cholesterol, serum sodium and protein intake.

²According to Subjective Global Assessment criteria.

³Adherence to protein intake recommendation was analysed. INR: International normalized ratio; MELD: Model for End-Stage Liver Disease.