Roles of hepatic stellate cells in acute liver failure: From the perspective of inflammation and fibrosis

Figure 2 Roles of hepatic stellate cells in liver failure. A: Hepatic stellate cells protect hepatocytes by participating in the maintenance of cell attachment and the architecture of liver tissue via extracellular matrix production; B: Hepatic stellate cells assist liver regeneration by producing growth factors; C: Hepatic stellate cells play a role in relaying inflammation signaling from sinusoids to parenchyma via the secretion of inflammatory cytokines.