Preoperative immunonutrition in patients undergoing liver resection: A prospective randomized trial

Table 2 Fatigue score and performance status measured at study entry, Day-1, POD 7 and POD 30 and grip strength measured at Day-1, POD7 and POD30 in patients who received either immunonutrition or standard care preoperatively

	Study entry	Day -1	POD 7	POD 30		P value1
					Group	Time	Group×Time
Fatigue score
STD group	4.2 ± 0.8	4.0 ± 0.6	7.1 ± 0.5	5.4 ± 0.7	0.121	< 0.0001	0.342
IMN group	4.3 ± 0.6	2.7 ± 0.4	6.7 ± 0.5	3.5 ± 0.8
Performance status
STD group	84.0 ± 3.9	85.7 ± 2.8	59.3 ± 4.2	73.5 ± 3.9	0.867	< 0.0001	0.810
IMN group	81.9 ± 2.8	86.8 ± 3.1	57.7 ± 4.8	75.0 ± 6.9
Grip strength (kg)
STD group	-	37.8 ± 2.7	35.4 ± 2.6	33.8 ± 2.3	0.825	0.019	0.849
IMN group	-	38.9 ± 3.4	36.5 ± 3.3	33.2 ± 2.4

¹Repeated measures analysis using the linear mixed model. Data are mean ± SE. POD: Postoperative day; IMN: Immunonutrition; STD: Standard care.