Comprehensive analysis of HFE gene in hereditary hemochromatosis and in diseases associated with acquired iron overload

Figure 2 Linkage disequilibrium among single nucleotide polymorphisms observed along the coding region of the HFE gene. Areas in dark gray represent strong linkage disequilibrium (LD) (LOD ≥ 2 and D' = 1), medium gray indicates moderate LD (LOD ≥ 2, D’ < 1), light gray indicates weak LD (LOD < 2, D' = 1); and white indicates no LD (LOD < 2, D’ < 1). Values of D' different from 1.00 are represented as a percentage within the square. LOD: Log of the odds; D': Linkage disequilibrium coefficient.