Necrolytic acral erythema in a human immunodeficiency virus/hepatitis C virus coinfected patient: A case report

Table 2 Literature review – cases of necrolytic acral erythema

	HCV	HIV	Zinc deficiency	Diagnosis	Treatment
Srisuwanwattana et al[1]	Yes	NA	No	Skin biopsy	Zinc supplementation and topical steroids
Kapoor et al[2]	Yes	NA	Yes	Clinical diagnosis	Oral zinc supplementation
Jakubovic et al[3]	No	NA	Yes	Skin biopsy	Nutritional Supplementation
Abdallah et al[5]	Yes	NA	No	Skin biopsy	Zinc supplementation
Pernet et al[7]	No	NA	No	Skin biopsy	Resolved spontaneously
Tabibian et al[8] Case 1	Yes	NA	Yes	Skin biopsy	Zinc supplementation
Tabibian et al[8] Case 2	Yes	NA	Yes	Skin biopsy	Zinc supplementation
Das et al[9]	No	NA	NA	Skin biopsy	Zinc supplementation
Najarian et al[12]	Yes	Yes	Yes	Skin biopsy	Zinc supplementation
Shumez et al[15]	Yes	NA	Yes	Skin biopsy	Zinc supplementation
Shaikh et al[16]	Yes	NA	No	Skin biopsy	Ledipasvir/sofosbuvir
Wu et al[17]	No	NA	NA	Skin biopsy	Systemic steroids
Rahman et al[18]	Yes	NA	NA	Skin biopsy	Systemic steroids and zinc supplementation
Botelho et al[19]	Yes	NA	Yes	Skin biopsy	Zinc supplementation
Panta et al[20]	No	NA	Low normal levels	Skin biopsy	Oral zinc supplementation and topical steroids
Pandit et al[21] Case 1	No	NA	Yes	Skin biopsy	Oral zinc supplementation
Pandit et al[21] Case 2	No	NA	Yes	Clinical diagnosis	Oral zinc supplementation

NA: Not available; HCV: Hepatitis C virus; HIV: Human immunodeficiency virus.