Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat

Figure 1 Influence of the multipotent stromal cells transplantation on mitotic activity of hepatocytes; Mitotic activity of hepatocytes in the residual livers at 3 (A, D), 7 (B, E) and 10 d (C, F) after the surgery; Mitotic index of hepatocytes is plotted against time after the surgery (G); HE staining. Arrowheads indicate mitotic figures in hepatocytes (A, B, D); Mitotic index of hepatocytes: Horizontal axis represents time elapsed after the surgery, vertical axis represents mitotic index of hepatocytes, ‰; White columns represent hepatocyte proliferation in the comparison group, gray columns represent hepatocyte proliferation in the multipotent stromal cells transplantation group; The data is presented as mean values with confidence intervals. SR: Subtotal resection; MSC: Multipotent stromal cells.