Impact of direct acting antivirals on occurrence and recurrence of hepatocellular carcinoma: Biologically plausible or an epiphenomenon?

doi:10.4254/wjh.v10.i2.267

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Feb 27, 2018 (publication date) through May 10, 2024

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hepatol. Feb 27, 2018; 10(2): 267-276
Published online Feb 27, 2018. doi: 10.4254/wjh.v10.i2.267

Table 1 Possible factors contributing to hepatocellular carcinoma after hepatitis C virus eradication by direct acting antivirals

Down regulation of IFN genes

Presence of fibrosis

Sudden disruption of chronic inflammatory state

Impaired immune response by NK cells

T cell dysfunction

Decreased microRNA-122

IFN: Interferon; NK: Natural killer.

Citation: Butt AS, Sharif F, Abid S. Impact of direct acting antivirals on occurrence and recurrence of hepatocellular carcinoma: Biologically plausible or an epiphenomenon? World J Hepatol 2018; 10(2): 267-276
URL: https://www.wjgnet.com/1948-5182/full/v10/i2/267.htm
DOI: https://dx.doi.org/10.4254/wjh.v10.i2.267