Bioengineered humanized livers as better three-dimensional drug testing model system

doi:10.4254/wjh.v10.i1.22

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 10, Issue 1

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6720)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-6) series.

Item

Count

PDF

387

WORD

260

HTML

4290

Figures (1-6)

186

Sum=5123

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

767

Download

816

Sum=1583

Jan 27, 2018 (publication date) through May 10, 2024

Times Cited of This Article

Times Cited (11)

Journal Information of This Article

Publication Name

World Journal of Hepatology

ISSN

1948-5182

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Hepatol. Jan 27, 2018; 10(1): 22-33
Published online Jan 27, 2018. doi: 10.4254/wjh.v10.i1.22

Full Size Figure Download Figure

Figure 4 Characterization of humanized liver. A: Optical image of humanized liver after 7 d of repopulation with human HPCs into a customized bioreactor; B: SEM image of humanized liver at day 7 showing cellular proliferation and natural arrangements; C: H and E staining of thin micro-section of humanized liver (Magnification: 10 ×); Albumin (D) and G6PC (E) immunofluorescence staining (green) representing the functional activity of repopulated human liver cells (Magnification: 20 ×); F: TUNEL staining of repopulated cells at day 7 (RL/d7) showed significantly high expression as compared with the negative control. SEM: Scanning electron microscopy.

Citation: Vishwakarma SK, Bardia A, Lakkireddy C, Nagarapu R, Habeeb MA, Khan AA. Bioengineered humanized livers as better three-dimensional drug testing model system. World J Hepatol 2018; 10(1): 22-33
URL: https://www.wjgnet.com/1948-5182/full/v10/i1/22.htm
DOI: https://dx.doi.org/10.4254/wjh.v10.i1.22