Vitamin D levels do not predict the stage of hepatic fibrosis in patients with non-alcoholic fatty liver disease: A PRISMA compliant systematic review and meta-analysis of pooled data

Table 6 Levels of sIL-2R, ALT, and HBV DNA in the sera of patients with chronic HBV infection (mean ± SD)

Study	Fibrosis stage used
NASH Clinical Research Network Scoring System Definition	Seven stages:
Kleiner et al[53], 2005	F0: No fibrosis
	F1a: Mild zone 3 sinusoidal fibrosis
	F1b: Moderated zone 3 sinusoidal fibrosis
	F1c: Peri-portal sinusoidal fibrosis
	F2: Zone 3 sinusoidal fibrosis and peri-portal sinusoidal fibrosis
	F3: Bridging fibrosis
	F4: Cirrhosis
Brunt et al[54], 1999	Stage 1: Zone 3 perisinusoidal/pericellular fibrosis; focally or extensively present
	Stage 2: Zone 3 perisinusoidal/pericellular fibrosis with focal or extensive periportal fibrosis
	Stage 3: Zone 3 perisinusoidal/pericellular fibrosis and portal fibrosis with focal or extensive bridging fibrosis
	Stage 4: Cirrhosis

NASH: Nonalcoholic steatohepatitis.