Effect of transplant center volume on post-transplant survival in patients listed for simultaneous liver and kidney transplantation

Table 1 Characteristics of recipients of liver transplant alone or simultaneous liver-kidney transplant

Variable1	Cases missing data	Received LTA (n = 393)	Received SLK (n = 4187)	P value2
		Mean (SD) or n (%)	Mean (SD) or n (%)
Transplant center SLKT volume	0	107 (± 83)	91 (± 66)	< 0.001
Transplant center LTA volume3	0	1187 (628)	1111 (627)	0.024
Age (yr)	0	54.2 (± 9.7)	54.8 (± 9.6)	0.279
Male	0	234 (60%)	2778 (66%)	0.007
Race	0			0.079
White		270 (69%)	2648 (63%)
Black		47 (12%)	639 (15%)
Other		76 (19%)	900 (22%)
Etiology of liver disease	0			0.004
Viral		114 (29%)	1182 (28%)
Cryptogenic		34 (9%)	330 (8%)
Autoimmune		31 (8%)	197 (5%)
NASH		43 (11%)	454 (11%)
Alcoholic		89 (23%)	982 (23%)
HCC		28 (7%)	376 (9%)
AHN		16 (4%)	85 (2%)
Other		38 (10%)	581 (14%)
Diabetes	65	123 (32%)	1665 (40%)	0.001
Dialysis	0	109 (28%)	1963 (47%)	< 0.001
BMI (kg/m2)	5	29.0 (± 5.9)	28.3 (± 5.9)	0.044
Serum creatinine (mg/dL)	5	2.8 (± 2.1)	3.8 (± 2.6)	< 0.001
Bilirubin (mg/dL)	5	8.2 (± 11.7)	5.7 (± 9.2)	< 0.001
Albumin (mg/dL)	6	3.0 (± 0.8)	3.0 (± 0.7)	0.074
INR	5	1.9 (± 1.4)	1.6 (± 0.7)	< 0.001
MELD score	16	25.6 (± 10.5)	25.2 (± 8.7)	0.445
eGFR	5	37.5 (± 27.2)	26.8 (± 22.4)	< 0.001
Hepatic encephalopathy on wait list	31	308 (79%)	2882 (69%)	< 0.001
Liver allograft cold ischemia time	213	6.8 (± 2.6)	6.8 (± 3.5)	0.706
Yr of transplant	0	2009 (4)	2010 (4)	< 0.001

¹Covariates assessed at wait listing, apart from center volume over study period, hepatic encephalopathy on the wait list, liver allograft cold ischemic time, and year of transplant;

²P value by independent t-test for continuous variables and χ² test for categorical variables;

³Includes all liver transplants, not limited to LTA among patients listed for SLK. Descriptive characteristics by recipients of liver transplant alone or simultaneous liver-kidney transplant among patients listed for liver and kidney transplant in 2002-2015 (n = 4580). SD: Standard deviation; SLK: Simultaneous liver-kidney transplant; LTA: Liver transplant alone; BMI: Body mass index; INR: International normalized ratio; MELD: Model for end-stage liver disease; eGFR: Estimated glomerular filtration rate.