Aggressive liver resection including major-vessel resection for colorectal liver metastases

Table 7 Univariate analysis for prognostic factors of the second resection

			Survival (%)
Variables		n	3 years	5 years	P value
Patient-related
Age (yr)	≤ 63	23	95.0	62.9	0.03
	≥ 64	21	67.9	34.5
Gender	Male	24	85.6	56.5	0.21
	Female	20	77.8	43.5
Primary-related
Site	Colon	33	82.9	49.1	0.80
	Rectum	11	80.0	54.9
Histology	Moderate	31	85.9	52.3	0.40
	Others	13	72.7	45.5
Dukes stage	A/B	14	71.4	38.1	0.15
	C	30	87.9	57.7
Liver-related
Distribution	Unilobar	32	79.1	46.5	0.63
	Bilobar	12	90.0	60.0
Number	1	24	76.1	40.0	0.61
	≥ 2	20	88.9	62.3
Maximum tumor size (mm)	≤ 30	22	73.3	47.5	0.41
	> 30	22	90.2	52.4
Prehepatectomy CEA (ng/mL)
	< 9	18	76.0	53.2	0.56
	≥ 9	18	93.8	67.7
Extrahepatic metastases	Present	9	77.8	62.2	0.99
	Absent	35	83.2	47.2
Treatment-related
Extent of hepatectomy	Major	10	90.0	64.3	0.02
	Minor	34	79.7	46.1
Tumor-free margin	Not exposed	37	81.2	53.9	0.39
	Exposed	7	85.7	34.3
Hepatectomy with ablation	Performed	3	66.7	33.3	0.98
	Not performed	41	83.3	52.2
Prehepatectomy chemotherapy
	Performed	6	50.0	50.0	0.73
	Not performed	38	80.0	50.0
Adjuvant chemotherapy	Performed	37	86.1	52.9	0.03
	Not performed	7	0.0	0.0
Combined resection	Performed	7	66.7	33.3	0.09
	Not performed	37	84.6	53.8
Major vessel invasion	Positive	4	33.3	0.0	< 0.01
	Negative	40	85.9	54.8

Moderate, moderately differentiated adenocarcinoma; CEA: Carcinoembryonic antigen.