Simultaneous occurrence of a hepatocellular carcinoma and a hepatic non-Hodgkin’s lymphoma infiltration

Figure 1 Contrast-computed tomographic (CT) scan shows a hyperdense (hypervascularised) lesion in the left lateral liver section, appearing hyperattenuating in the early arterial phase of contrast enhanced CT.

Figure 2 Magnetic resonance imaging shows an early enhancing mass in the left lateral segments of the liver.

Figure 3 Immunohistochemical examination of the atypical small lymphocytic infiltrate in portal tracts. A: CD20; B: CD3; C: CD5; D: CD23.

Figure 4 Macroscopical view of the liver parenchyma and the tumor mass. A: Macroscopically liver parenchyma shows prominent enhanced greyish portal tracts; B: An at most 4.8 cm measuring tumorous nodular lesion.

Figure 5 Histological specimen. A: Border of non-neoplastic liver parenchyma (upper left) and hepatocellular carcinoma (HCC) (lower right); B: Trabecular configured HCC with atypical lymphocytic infiltration by the B-cell lineage (B-CLL); C: Portal tracts are rounded and show an atypical dense lymphocytic infiltration by B-CLL; D: There is neither significant fibrosis nor cirrhosis in liver parenchyma (van Gieson stain).