Current progress in use of adipose derived stem cells in peripheral nerve regeneration

Table 1 Summary of seddon and sunderland classifications following peripheral nerve injury adapted from[98]

Sunderland	Seddon	Injury	Neurosensory impairment	Recovery potential
I	Neuropraxia	Intrafascicular oedema, conduction block Segmental demyelination	Neuritis, paraesthesia Neuritis, paraesthesia	Ful (1-7 d) Full (1-2 mo)
II III IV	Axonotmesis	Axons severed, endoneurial tube intact Endoneurial tube torn Only epineurium intact	Paraesthesia, episodic dysesthesia Paraesthesia Hypoaesthesia, dysaesthesia neuroma	Full (2-4 mo) Slow, Incomplete (12 mo) Neuroma
V	Neurotmesis	Loss of continuity	Anaesthesia, extreme pain and neuroma formation	None
VI		As per V	As per V	Nil