Impact of the antiproliferative agent ciclopirox olamine treatment on stem cells proteome

Table 4 Proteins which are downregulated upon ciclopirox olamine treatment compared to control

	k/CPX
	ESC	maGSC
Acp1	1.29	6.01
Acy11	1.38	2.81
Akr1b1	2.07	13.44
Aprt1	4.80	3.60
Atp5a11	3.50	1.21
Capzb	3.04	2.35
Cbx31	1.72	2.12
Cct21	12.00	1.28
Cct51	1.06	2.02
Eef1a11	2.47	1.74
Eef1d1	1.46	2.03
Eif5a1	1.31	2.07
Eno11	3.56	1.60
Fscn1	3.31	1.49
Glod4	3.35	1.60
Gnb2l1	2.61	12.92
Hist1h2bb	2.31	2.10
Hist2h2ac	17.33	67.90
Hnrnpab1	2.41	3.36
Hnrnpk1	2.00	1.17
Hsp90aa11	1.19	6.79
Hsp90aa11	1.84	3.02
Hspa41	3.28	1.51
Hspa4	1.13	3.14
Hspa8	1.74	7.17
Hspd1	1.67	3.07
Impdh21	2.59	2.13
Impdh21	> 100	27.94
Krt181	2.31	1.44
Lgals2	2.82	8.45
Ncl1	1.33	2.61
Nit2	1.24	2.13
Nme11	6.25	1.56
Nme21	4.77	4.51
Pcbp11	2.21	1.64
Pkm21	3.75	3.27
Pnp1	1.20	2.62
Psmb41	1.01	2.32
Ruvbl11	1.02	2.14
Srm	1.64	3.63
Shmt11	> 100	> 100
Tardbp1	1.38	3.52
Tcp1	1.47	3.76
Tuba1c1	1.87	3.11
Tubb2c1	1.38	3.41
Ube2n1	1.31	6.45
Uchl11	2.66	1.66

¹The proteins are referred to in the text and following tables. CPX: Ciclopirox olamine; ESC: Embryonic stem cell; maGSC: Multipotent adult germline stem cell.