Dynamic culture improves MSC adhesion on freeze-dried bone as a scaffold for bone engineering

Figure 4 Histological analysis of the interaction between mesenchymal stem cells and freeze-dried bone in two different cultivation systems (HE stain, × 200). A: Mesenchymal stem cells (MSCs) adhered on the bone surface after dynamic culture. The dynamic co-culture allowed the formation of multiple cell layers; B: MSCs adhered on the bone surface after static culture. There is no formation of multiple cell layers after static co-culture. FDB: Freeze-dried bone.