MED12 mutation activates Notch signaling to enhance cancer stemness and suppress CD8+ T cell cytotoxicity in lung cancer

Figure 4 Analysis of the association between mediator complex subunit 12 expression and immune cell infiltration based on The Cancer Genome Atlas transcriptomic data. A: Bar plot showing immune cell abundances in lung cancer samples with high and low mediator complex subunit 12 (MED12) expression; B: Correlation between MED12 expression and immune cell enrichment across pan-cancer; C-G: Scatter plots showing the correlation of MED12 expression with CD8+ T cells (C), T cells (D), macrophages (E), dendritic cells (F), and mast cells (G) in lung cancer patients. ^aP < 0.05. MED12: Mediator complex subunit 12; DC: Dendritic cell.