Very small embryonic-like stem cells: A predictor synergizing with complement and inflammatory factors for immunoglobulin A nephropathy prognosis

doi:10.4252/wjsc.120694

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World Journal of Stem Cells

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1948-0210

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World J Stem Cells. Aug 26, 2026; 18(8): 120694
Published online Aug 26, 2026. doi: 10.4252/wjsc.120694

Table 3 Logistic regression model was used to analyze the influencing factors of end-stage renal disease occurrence in patients with immunoglobulin A nephropathy

Index	Univariate analysis		Multivariate analysis
Index	OR (95%CI)	P value	OR (95%CI)	P value
S1	0.376 (0.172-0.823)	0.014^a	0.019 (0.001-0.485)	0.016^a
Uric acid	1.022 (1.009-1.034)	< 0.001^a	1.160 (0.902-1.492)	0.246
CFB	0.995 (0.991-1.000)	0.040^a	0.987 (0.972-1.004)	0.128
CFI	0.938 (0.896-0.981)	0.006^a	0.656 (0.492-0.874)	0.004^a
C3a	0.989 (0.984-0.993)	< 0.001^a	0.970 (0.947-0.992)	0.009^a
MCP-1	1.019 (1.011-1.028)	< 0.001^a	1.032 (1.000-1.066)	0.051
IL-6	1.266 (1.141-1.404)	< 0.001^a	0.260 (0.023-2.895)	0.273
TNF-α	1.400 (1.238-1.583)	< 0.001^a	2.055 (1.262-3.347)	0.004^a
VSELs	1.159 (1.095-1.226)	< 0.001^a	1.859 (1.022-3.381)	0.042^a

^aP < 0.05.

OR: Odds ratio; CI: Confidence interval; CFB: Complement factor B; CFI: Complement factor I; MCP-1: Monocyte chemoattractant protein-1; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; VSELs: Very small embryonic-like stem cells.

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Citation: Lou CL, Ren KX, Xu XQ, Wang XJ, Fan XP, Feng B, Hu PX, Zhou YJ. Very small embryonic-like stem cells: A predictor synergizing with complement and inflammatory factors for immunoglobulin A nephropathy prognosis. World J Stem Cells 2026; 18(8): 120694
URL: https://www.wjgnet.com/1948-0210/full/v18/i8/120694.htm
DOI: https://dx.doi.org/10.4252/wjsc.120694

Lou CL, Ren KX, Xu XQ, Wang XJ, Fan XP, Feng B, Hu PX, Zhou YJ. Very small embryonic-like stem cells: A predictor synergizing with complement and inflammatory factors for immunoglobulin A nephropathy prognosis. World J Stem Cells 2026; 18(8): 120694 [DOI: 10.4252/wjsc.120694]

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