Protective effect of hUC-MSCs regulating peritoneal mesothelial cell EMT through cGAS-STING signaling pathway in high glucose-induced peritoneal fibrosis

Figure 2 Effects of human umbilical cord-derived mesenchymal stem cells on migration and invasion of high glucose-treated HMrSV5 cells. A: Identification of human umbilical cord-derived mesenchymal stem cell surface markers via flow symmetry (negative markers: CD34, CD45; positive markers: CD29, CD44); B and C: Migration ability of HMrSV5 cells assessed via wound healing assay and corresponding quantitative analysis; D and E: Invasion ability of different HMrSV5 cells assessed via Transwell assay and corresponding quantitative analysis. Data are presented as mean ± SD. ^aP < 0.05 vs control; ^bP < 0.05 vs high glucose. hUC-MSCs: Human umbilical cord-derived mesenchymal stem cells; HG: High glucose; CD34: Cluster of differentiation 34; CD45: Leukocyte common antigen; CD29: Integrin beta 1; CD44: CD44 antigen.