Maximizing stem cell yield from limited adipose tissue: A novel two-step digestion approach and future artificial intelligence-integrated perspectives

doi:10.4252/wjsc.120206

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Aug 26, 2026; 18(8): 120206
Published online Aug 26, 2026. doi: 10.4252/wjsc.120206

Table 3 Comparison of different collagenase types in liposuction-related cell isolation

Collagenase type	Cell yield	Cell viability	Surface marker retention	Clinical safety	Recommended rating
Collagenase type I	★★★★★	★★★★☆	★★★★	★★	★★★★★
Collagenase type II	★★★☆	★★★	★★★	★★	★★☆
Collagenase type IV	★★★	★★★★	★★★★★	★★	★★★
Collagenase I + dispase/thermolysin	★★★★★	★★★★	★★★★	★★	★★★★
Recombinant/GMP-grade collagenase	★★★★☆	★★★★★	★★★★★	★★★★★	★★★★★

This table uses a five-star rating system to evaluate and compare different performance in each aspect. Higher star ratings indicating better performance. GMP: Good manufacturing practices.

Full Size Table

Citation: Wu YF, Jiang X, Zhang JG, Zhang W. Maximizing stem cell yield from limited adipose tissue: A novel two-step digestion approach and future artificial intelligence-integrated perspectives. World J Stem Cells 2026; 18(8): 120206
URL: https://www.wjgnet.com/1948-0210/full/v18/i8/120206.htm
DOI: https://dx.doi.org/10.4252/wjsc.120206

Wu YF, Jiang X, Zhang JG, Zhang W. Maximizing stem cell yield from limited adipose tissue: A novel two-step digestion approach and future artificial intelligence-integrated perspectives. World J Stem Cells 2026; 18(8): 120206 [DOI: 10.4252/wjsc.120206]

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