Copyright: ©Author(s) 2026.
World J Stem Cells. Aug 26, 2026; 18(8): 119963
Published online Aug 26, 2026. doi: 10.4252/wjsc.119963
Published online Aug 26, 2026. doi: 10.4252/wjsc.119963
Figure 1 Human amniotic mesenchymal stem cell-derived small extracellular vesicles promote bone regeneration in irradiated tissue by delivering mitochondria, microRNAs, and signaling molecules to restore energy metabolism, reprogram progenitor cells, and shift mac rophages from pro-inflammatory to anti-inflammatory phenotypes.
hAMSC-sEVs: Human amniotic mesenchymal stem cell-derived small extracellular vesicles; miRNA: MicroRNA; RUNX2: Runt-related transcription factor 2.
- Citation: Yang Y, Zhang GD, Yi L, Yang X, Han ZG, Song CY, Lu JS, Wang KY. Breaking the cycle of radiation-induced bone death: Human amniotic mesenchymal stem cell-derived small extracellular vesicles restore coupled osteo-angiogenic regeneration. World J Stem Cells 2026; 18(8): 119963
- URL: https://www.wjgnet.com/1948-0210/full/v18/i8/119963.htm
- DOI: https://dx.doi.org/10.4252/wjsc.119963