Stem cell-based strategies for hearing restoration: Current advances and future perspectives

doi:10.4252/wjsc.122823

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Jul 26, 2026; 18(7): 122823
Published online Jul 26, 2026. doi: 10.4252/wjsc.122823

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Figure 3 Evolution of stem cell-related strategies for hearing restoration from 1990 to 2025. The timeline summarizes the emergence and major progress of key strategies, including pluripotent stem cell-derived auditory cells, endogenous reprogramming, mesenchymal stem/stromal cell/extracellular vesicle-based therapies, cochlear organoids, spiral ganglion neuron/circuit repair, and bioengineering-assisted cochlear implant integration. PSC: Pluripotent stem cell; MSC: Mesenchymal stem/stromal cell; EV: Extracellular vesicle; SGN: Spiral ganglion neuron; hESC: Human embryonic stem cell; hPSC: Human pluripotent stem cell.

Citation: Qu YJ, Wang JY, Wang Z, Yao W, Xia ZF. Stem cell-based strategies for hearing restoration: Current advances and future perspectives. World J Stem Cells 2026; 18(7): 122823
URL: https://www.wjgnet.com/1948-0210/full/v18/i7/122823.htm
DOI: https://dx.doi.org/10.4252/wjsc.122823

Qu YJ, Wang JY, Wang Z, Yao W, Xia ZF. Stem cell-based strategies for hearing restoration: Current advances and future perspectives. World J Stem Cells 2026; 18(7): 122823 [DOI: 10.4252/wjsc.122823]

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