Efficacy and safety of cell-based regenerative therapies for fistula-related diseases: An umbrella review of systematic reviews

doi:10.4252/wjsc.122048

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Jul 26, 2026; 18(7): 122048
Published online Jul 26, 2026. doi: 10.4252/wjsc.122048

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Figure 2 Evidence bubble plot of comparative effects of regenerative therapies vs control. MSC: Mesenchymal stem cell; AD-MSC: Adipose-derived mesenchymal stem cell; BM-MSC: Bone marrow-derived mesenchymal stem cell; PF: Perianal fistulas; FCD: Fistulizing Crohn’s disease; PDAI: Perianal disease activity index; AE: Adverse event; GRADE: Grading of Recommendations, Assessment, Development and Evaluation; W: week(s).

Citation: Duan YL, Wen YH, Chen SA, Nie R, Pang MQ, Deng MJ, Wang ZX, Fan HN. Efficacy and safety of cell-based regenerative therapies for fistula-related diseases: An umbrella review of systematic reviews. World J Stem Cells 2026; 18(7): 122048
URL: https://www.wjgnet.com/1948-0210/full/v18/i7/122048.htm
DOI: https://dx.doi.org/10.4252/wjsc.122048

Duan YL, Wen YH, Chen SA, Nie R, Pang MQ, Deng MJ, Wang ZX, Fan HN. Efficacy and safety of cell-based regenerative therapies for fistula-related diseases: An umbrella review of systematic reviews. World J Stem Cells 2026; 18(7): 122048 [DOI: 10.4252/wjsc.122048]

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