Exosomal miR-181d-5p promotes spinal cord injury repair by driving microglial polarization from M1 to M2 phenotype

doi:10.4252/wjsc.119260

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Jul 26, 2026; 18(7): 119260
Published online Jul 26, 2026. doi: 10.4252/wjsc.119260

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Figure 3 Identification of miR-181d-5p as a key regulator in exosome-mediated effects. A: MicroRNA expression profiles in primary microglia from different treatment groups were analyzed by polymerase chain reaction array and presented as a heatmap; B: The expression level of miR-181d-5p in microglia under different treatments was determined by reverse transcription and quantitative polymerase chain reaction. Data are presented as mean ± SD. LPS: Lipopolysaccharide; Exo: Exosome.

Citation: Wang W, Wang B, Yin H. Exosomal miR-181d-5p promotes spinal cord injury repair by driving microglial polarization from M1 to M2 phenotype. World J Stem Cells 2026; 18(7): 119260
URL: https://www.wjgnet.com/1948-0210/full/v18/i7/119260.htm
DOI: https://dx.doi.org/10.4252/wjsc.119260

Wang W, Wang B, Yin H. Exosomal miR-181d-5p promotes spinal cord injury repair by driving microglial polarization from M1 to M2 phenotype. World J Stem Cells 2026; 18(7): 119260 [DOI: 10.4252/wjsc.119260]

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