Cancer stem cell-associated markers and their prognostic value in non-small cell lung cancer

doi:10.4252/wjsc.119550

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World Journal of Stem Cells

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1948-0210

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World J Stem Cells. Jun 26, 2026; 18(6): 119550
Published online Jun 26, 2026. doi: 10.4252/wjsc.119550

Table 1 Comparison of general information in different cancer stem cell groups, n (%)/mean ± SD

Variables	Low CSC group (n = 85)	High CSC group (n = 115)	Statistical values	P value
Age (years)	62.05 ± 8.85	64.15 ± 9.10	t = 1.632	0.104
Gender
Male	58 (68.24)	68 (59.13)	χ² = 1.738	0.187
Female	27 (31.76)	47 (40.87)	χ² = 1.738	0.187
History of smoking
Yes	48 (56.47)	70 (60.87)	χ² = 0.391	0.532
No	37 (43.53)	45 (39.13)	χ² = 0.391	0.532
Maximum tumor diameter (cm)	3.15 ± 1.20	3.75 ± 1.35	t = 3.255	0.001
Histological type
Adenocarcinoma	70 (82.35)	58 (50.43)	χ² = 21.611	< 0.001
Non-adenocarcinoma	15 (17.65)	57 (49.57)	χ² = 21.611	< 0.001
Differentiation degree
Poorly	24 (28.24)	48 (41.74)	χ² = 3.868	0.049
Moderately to well	61 (71.76)	67 (58.26)	χ² = 3.868	0.049
Lymph node metastasis
Positive	28 (32.94)	56 (48.70)	χ² = 4.980	0.026
Negative	57 (67.06)	59 (51.30)	χ² = 4.980	0.026
TNM staging
Stage I-II	67 (78.82)	75 (65.22)	χ² = 4.394	0.036
Stage III	18 (21.18)	40 (34.78)	χ² = 4.394	0.036
Postoperative adjuvant therapy
Yes	38 (44.71)	48 (41.74)	χ² = 0.176	0.675
No	47 (55.29)	67 (58.26)	χ² = 0.176	0.675

CSC: Cancer stem cell; TNM: Tumor-node-metastasis.

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Citation: Luo LL, Jiang SC, Li S, Zhang GY, Tang JJ, Guo YD. Cancer stem cell-associated markers and their prognostic value in non-small cell lung cancer. World J Stem Cells 2026; 18(6): 119550
URL: https://www.wjgnet.com/1948-0210/full/v18/i6/119550.htm
DOI: https://dx.doi.org/10.4252/wjsc.119550

Luo LL, Jiang SC, Li S, Zhang GY, Tang JJ, Guo YD. Cancer stem cell-associated markers and their prognostic value in non-small cell lung cancer. World J Stem Cells 2026; 18(6): 119550 [DOI: 10.4252/wjsc.119550]

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