Dysregulated circARF3/miR-27b-3p/YAP1 contributes to impaired osteogenic differentiation of periodontal ligament stem cells in periodontitis

doi:10.4252/wjsc.116004

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Jun 26, 2026; 18(6): 116004
Published online Jun 26, 2026. doi: 10.4252/wjsc.116004

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Figure 6 Circular RNA ADP-ribosylation factor 3 affects periodontal ligament stem cell osteogenic differentiation via miR-27b-3p/Yes associated protein 1 axis. A and B: Alkaline phosphatase and alizarin red staining of periodontal ligament stem cells; C and D: Expression of osteoblast makers, Runx2, Osterix, Osteocalcin and Col1a1 was determined by western blotting assay. ^bP < 0.01, compared with ovNC group; ^cP < 0.01, compared with ovARF3 group. ARF3: ADP-ribosylation factor 3; ARS: Alizarin red staining; ALP: Alkaline phosphatase.

Citation: Qi L, Wang XQ, Sun J, Li RZ, Mao ZB. Dysregulated circARF3/miR-27b-3p/YAP1 contributes to impaired osteogenic differentiation of periodontal ligament stem cells in periodontitis. World J Stem Cells 2026; 18(6): 116004
URL: https://www.wjgnet.com/1948-0210/full/v18/i6/116004.htm
DOI: https://dx.doi.org/10.4252/wjsc.116004

Qi L, Wang XQ, Sun J, Li RZ, Mao ZB. Dysregulated circARF3/miR-27b-3p/YAP1 contributes to impaired osteogenic differentiation of periodontal ligament stem cells in periodontitis. World J Stem Cells 2026; 18(6): 116004 [DOI: 10.4252/wjsc.116004]

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