From laboratory to clinic: Bridging regulatory and manufacturing gaps in stem cell-based therapies

doi:10.4252/wjsc.v18.i5.117591

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. May 26, 2026; 18(5): 117591
Published online May 26, 2026. doi: 10.4252/wjsc.v18.i5.117591

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Figure 3 A diagrammatic representation of a scalable cell culture process utilizing the CliniMACS Prodigy platform is presented. In this workflow, cells are cultured on microcarriers inside a bioreactor, subsequently undergoing growth within an automated, closed system. Critical environmental factors such as pH, dissolved oxygen, and nutrient levels are continuously monitored and regulated to maintain ideal conditions for consistent cell proliferation and reproducibility.

Citation: Ebrahim NAA, Farghaly TA, Masaret GS, Alsaedi AMR, Soliman SMA. From laboratory to clinic: Bridging regulatory and manufacturing gaps in stem cell-based therapies. World J Stem Cells 2026; 18(5): 117591
URL: https://www.wjgnet.com/1948-0210/full/v18/i5/117591.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i5.117591

Ebrahim NAA, Farghaly TA, Masaret GS, Alsaedi AMR, Soliman SMA. From laboratory to clinic: Bridging regulatory and manufacturing gaps in stem cell-based therapies. World J Stem Cells 2026; 18(5): 117591 [DOI: 10.4252/wjsc.v18.i5.117591]

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