Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells

doi:10.4252/wjsc.v18.i5.117241

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. May 26, 2026; 18(5): 117241
Published online May 26, 2026. doi: 10.4252/wjsc.v18.i5.117241

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Figure 7 Angiogenic potential of adipose tissue derived mesenchymal stem cells. A: Young adipose tissue derived mesenchymal stem cells (ADMSCs) displayed extensive tubular networks (20 ×); B: Aged normoxia ADMSCs showed delayed and poor tube formation, with sparse and weakly connected tubular structures (20 ×); C: Aged hypoxia ADMSCs group displayed significantly improved angiogenesis with more interconnected and branched networks compared with aged hypoxia ADMSCs (20 ×); D-F: Number of nodes (D), mesh area (E), total branching length (F) decreased in aged normoxia ADMSCs group. Presentation of data as mean ± SD (n = 3). NS: Not significant.

Citation: Bashir B, Choudhery MS, Hussain I. Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells. World J Stem Cells 2026; 18(5): 117241
URL: https://www.wjgnet.com/1948-0210/full/v18/i5/117241.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i5.117241

Bashir B, Choudhery MS, Hussain I. Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells. World J Stem Cells 2026; 18(5): 117241 [DOI: 10.4252/wjsc.v18.i5.117241]

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