Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells

doi:10.4252/wjsc.v18.i5.117241

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. May 26, 2026; 18(5): 117241
Published online May 26, 2026. doi: 10.4252/wjsc.v18.i5.117241

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Figure 3 Clonogenic potential of mesenchymal stem cells under hypoxic and normoxic conditions. A: Total number of colony-forming units (CFUs); B: Plating efficiency (PE). Young adipose tissue derived mesenchymal stem cells (ADMSCs) displayed more CFUs and higher PE as compared to aged normoxic ADMSCs and aged hypoxic ADMSCs. Hypoxic preconditioning significantly improved both CFU number and PE in aged ADMSCs. Data are presented as mean ± SD. ^aP < 0.05, ^dP < 0.0001. CFU: Colony-forming unit.

Citation: Bashir B, Choudhery MS, Hussain I. Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells. World J Stem Cells 2026; 18(5): 117241
URL: https://www.wjgnet.com/1948-0210/full/v18/i5/117241.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i5.117241

Bashir B, Choudhery MS, Hussain I. Hypoxic preconditioning restores the regenerative potential of aged adipose tissue derived mesenchymal stem cells. World J Stem Cells 2026; 18(5): 117241 [DOI: 10.4252/wjsc.v18.i5.117241]

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