Hypoxia-conditioned extracellular vesicles from human amniotic membrane stem cells attenuate D-galactose-induced aging in mice

Figure 1 Characteristics of extracellular vesicles obtained from amniotic membrane stem cells. A: Size distribution of extracellular vesicle particles from nanoparticle-tracking analysis; B: Concentrations of growth factors and neurotrophic factors in normoxic (white bars) and hypoxic (black bars) culture extracellular vesicles. ^aP < 0.05, compared with each normoxic culture extracellular vesicles. BDNF: Brain-derived neurotrophic factor; NGF: Nerve growth factor; PDGF: Platelet-derived growth factor; IGF: Insulin-like growth factor; VEGF: Vascular endothelial growth factor.