Hypoxia-conditioned extracellular vesicles from human amniotic membrane stem cells attenuate D-galactose-induced aging in mice

doi:10.4252/wjsc.v18.i4.117707

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Apr 26, 2026; 18(4): 117707
Published online Apr 26, 2026. doi: 10.4252/wjsc.v18.i4.117707

Table 2 Lipidome analysis

Lipid classes	Class	AMSC	UCBSC (reference)
Ceramide	Cer	14.31	1.52
Diacylglycerol	DG	0.90	0.53
Monohexosylceramide	HEX1 Cer	0.18	0.38
Dihexosylceramide	HEX2 Cer	ND	0.05
Lysophosphatidylcholine	LPC	2.37	1.77
Lysophosphatidylglycerol	LPG	0.00	ND
Lysophosphatidylinositol	LPI	0.00	1.30
Monoglyceride	MG	1.70	0.42
Phosphatidic acid	PA	0.00	ND
Phosphatidylcholine	PC	71.89	51.70
Phosphatidylethanolamine	PE	6.70	3.83
Phosphatidylglycerol	PG	0.00	0.87
Phosphatidylinositol	PI	0.00	10.36
Phosphatidylserine	PS	0.00	3.92
Sphingomyelin	SM	0.32	21.44
Triacylglycerol	TG	1.63	0.40
	Total	100.00	98.49

AMSC: Amniotic membrane stem cell; UCBSC: Umbilical cord blood stem cell; ND: Not detected.

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Citation: Tsolmon KE, Bavuu Z, Kim SS, Jeong HS, Park D, Kim YB. Hypoxia-conditioned extracellular vesicles from human amniotic membrane stem cells attenuate D-galactose-induced aging in mice. World J Stem Cells 2026; 18(4): 117707
URL: https://www.wjgnet.com/1948-0210/full/v18/i4/117707.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i4.117707

Tsolmon KE, Bavuu Z, Kim SS, Jeong HS, Park D, Kim YB. Hypoxia-conditioned extracellular vesicles from human amniotic membrane stem cells attenuate D-galactose-induced aging in mice. World J Stem Cells 2026; 18(4): 117707 [DOI: 10.4252/wjsc.v18.i4.117707]

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