Mesenchymal stem cells alleviate renal injury of lupus nephritis mice by reconstructing the immune microenvironment of renal tissue

Figure 6 Changes in the percentages of immune cells after coculture of umbilical cord mesenchymal stem cells and peripheral blood mononuclear cells. A: Flow cytometry was used to analyse the proliferation of Carboxy Fluorescein Succinimidyl Ester-labelled lymphocytes and changes in the percentages of T helper 1 (TH1), TH17, and regulatory T cells after coculture of umbilical cord mesenchymal stem cells and peripheral blood mononuclear cell; B: Quantitative analysis of the percentages of TH1 cells, TH17 cells and regulatory T after co-culture of umbilical cord mesenchymal stem cells and peripheral blood mononuclear cell. All data was expressed as mean ± SEM, ^aP < 0.05 vs lupus nephritis group, ^cP < 0.001 vs lupus nephritis group. TH1: T helper 1; Treg: Regulatory T; IFN: Interferon; IL: Interleukin; CFSE: Carboxy Fluorescein Succinimidyl Ester; UCMSCs: Umbilical cord mesenchymal stem cells.