Mesenchymal stem cells alleviate renal injury of lupus nephritis mice by reconstructing the immune microenvironment of renal tissue

Figure 3 Results of renal tissue pathology and electron microscopy. A: Pathological and electron microscopy results of renal tissue. Hematoxylin and eosin staining (1^st line, 400 ×), periodic acid-Schiff staining (2^nd line, 400 ×), Masson’s trichrome staining (3^rd line, 400 ×) and electron microscopy (4^th line, 12000 ×). Normal group (1^st column), lupus nephritis group (2^nd column), and umbilical cord mesenchymal stem cells group (3^rd column) were used; B: Immunohistochemical staining and statistical results of CD3, CD68 and B220 in mice kidney tissue. All data was expressed as mean ± SEM, ^bP < 0.01 vs lupus nephritis group, ^cP < 0.001 vs lupus nephritis group. LN: Lupus nephritis; UCMSCs: Umbilical cord mesenchymal stem cells; HE: Hematoxylin and eosin; PAS: Periodic acid-Schiff.