Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders

doi:10.4252/wjsc.v18.i3.116226

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World Journal of Stem Cells

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1948-0210

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Mar 26, 2026; 18(3): 116226
Published online Mar 26, 2026. doi: 10.4252/wjsc.v18.i3.116226

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Figure 1 Exosomes biogenesis. Exosomes fuse with the plasma membrane after being generated within multivesicular endosomes during intraluminal vesicle production and are subsequently released through exocytosis. In an alternative mechanism, lysosome fusion, the multivesicular endosome merges with a lysosome to undergo degradation rather than exosome discharge. Ectocytosis causes microvesicles to form directly from the plasma membrane.

Citation: Choudhery MS, Arif T, Mahmood R, Harris DT. Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders. World J Stem Cells 2026; 18(3): 116226
URL: https://www.wjgnet.com/1948-0210/full/v18/i3/116226.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i3.116226

Choudhery MS, Arif T, Mahmood R, Harris DT. Stem cell derived exosomes: Emerging cell-free therapeutics for neurodegenerative disorders. World J Stem Cells 2026; 18(3): 116226 [DOI: 10.4252/wjsc.v18.i3.116226]

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