Alpha-ketoglutarate enhances adipose-derived stem cells survival in wound healing by hypoxia-inducible factor 1-alpha-mediated redox homeostasis and glycogen-dependent bioenergetics

doi:10.4252/wjsc.v18.i2.113694

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 2

This Article

(44)

(55)

(0)

(15)

(1)

(1115)

(1)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Stem Cells

ISSN

1948-0210

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

World J Stem Cells. Feb 26, 2026; 18(2): 113694
Published online Feb 26, 2026. doi: 10.4252/wjsc.v18.i2.113694

Full Size Figure Download Figure

Figure 1 Alpha-ketoglutarate improves cell survival and burn wound healing. A: Terminal deoxynucleotidyl transferase dUTP nick end labeling immunostaining of the mouse burn wounds treated with adipose-derived stem cells (ADSCs) and α-ketoglutarate-ADSCs (αKG-ADSCs), with quantification; B: Ex vivo annexin V-propidium iodide flow-cytometry analysis of CM-FDA-labeled mouse ADSCs and αKG-ADSCs; C: Representative images of hypoxyprobe (upper panel) and 8-hydroxy-2’-deoxyguanosine (lower panel) immunostaining of mouse ADSCs and αKG-ADSCs, with quantification; D: Hematoxylin-eosin staining of the mouse burn wounds treated with ADSCs and αKG-ADSCs. Data are presented with means ± SEM (^aP < 0.05). ADSCs: Adipose-derived stem cells; αKG-ADSCs: Alpha-ketoglutarate adipose-derived stem cells.

Citation: Dilimulati D, Dilimulati D, Cui L. Alpha-ketoglutarate enhances adipose-derived stem cells survival in wound healing by hypoxia-inducible factor 1-alpha-mediated redox homeostasis and glycogen-dependent bioenergetics. World J Stem Cells 2026; 18(2): 113694
URL: https://www.wjgnet.com/1948-0210/full/v18/i2/113694.htm
DOI: https://dx.doi.org/10.4252/wjsc.v18.i2.113694

Dilimulati D, Dilimulati D, Cui L. Alpha-ketoglutarate enhances adipose-derived stem cells survival in wound healing by hypoxia-inducible factor 1-alpha-mediated redox homeostasis and glycogen-dependent bioenergetics. World J Stem Cells 2026; 18(2): 113694 [PMID: 41808885 DOI: 10.4252/wjsc.v18.i2.113694]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.